Ameloblastin and amelogenin expression in posnatal developing mouse molars
نویسندگان
چکیده
منابع مشابه
Tracking Endogenous Amelogenin and Ameloblastin In Vivo
Research on enamel matrix proteins (EMPs) is centered on understanding their role in enamel biomineralization and their bioactivity for tissue engineering. While therapeutic application of EMPs has been widely documented, their expression and biological function in non-enamel tissues is unclear. Our first aim was to screen for amelogenin (AMELX) and ameloblastin (AMBN) gene expression in mandib...
متن کاملAnalysis of co-assembly and co-localization of ameloblastin and amelogenin
Epithelially-derived ameloblasts secrete extracellular matrix proteins including amelogenin, enamelin, and ameloblastin. Complex intermolecular interactions among these proteins are believed to be important in controlling enamel formation. Here we provide in vitro and in vivo evidence of co-assembly and co-localization of ameloblastin with amelogenin using both biophysical and immunohistochemic...
متن کاملThe ultrastructure of intradental nerves in developing mouse molars.
The purpose of this investigation was to study the nerves in mouse molar teeth during their development to observe their distribution and their relationship to the odontoblast and its process. The specimens were first assessed by light microscopy using silver staining techniques. It was found that by nine days after birth, major nerves appeared in the pulp organ and extended to the basal region...
متن کاملAmeloblastin peptide encoded by exon 5 interacts with amelogenin N-terminus
Interactions between enamel matrix proteins are important for enamel biomineralization. In recent in situ studies, we showed that the N-terminal proteolytic product of ameloblastin co-localized with amelogenin around the prism boundaries. However, the molecular mechanisms of such interactions are still unclear. Here, in order to determine the interacting domains between amelogenin and ameloblas...
متن کاملComparative temporospatial expression profiling of murine amelotin protein during amelogenesis.
Tooth enamel is formed in a typical biomineralization process under the guidance of specific organic components. Amelotin (AMTN) is a recently identified, secreted protein that is transcribed predominantly during the maturation stage of enamel formation, but its protein expression profile throughout amelogenesis has not been described in detail. The main objective of this study was to define th...
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ژورنال
عنوان ژورنال: Journal of Oral Science
سال: 2005
ISSN: 1343-4934,1880-4926
DOI: 10.2334/josnusd.47.27